Warm Global Customers With China Plastic Machinery

A galantamine bis(hydroxynaphthyl) sustained-release microparticle for injection and its preparation method

The present invention discloses sustained-release microspheres of galantamine embonate for injection and a preparation method thereof. The microspheres comprise galantamine embonate, a lactide-glycolide copolymer, and a weakly alkaline additive, and are prepared by a hot-melt extrusion combined with low-temperature pulverization technology. Compared with the prior art, the microspheres prepared by the present invention have low initial burst release, sufficient drug release, low moisture content, simple preparation process, high product yield and encapsulation efficiency, and are suitable for industrial production.

Area Code: CN

Application Number: CN202010179270.9


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